Question from Karl - Possibility that Henry VIII was the cause of the high mortality of his offspring
Henry VIII had little luck in establishing his dynasty. The number of miscarriages and stillbirths that his wives suffered seem excessive, even taking into account the time period when there was a high mortality. This is in sharp contrast to other contemporary royals, and even Henry's mother, Elizabeth of York. Would it be possible for the fault to lie with Henry himself? This would mean that Henry carried a balanced translocation, probably a new mutation. This could explain the miscarriages, stillbirths and possibly early death from cancer of Mary Tudor. If this were considered possible, would there be any way of extracting DNA to check this hypothesis.